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Vitamin D, Covid, and Skin Color

  • What is Vitamin D?
  • Does Vitamin D Protect Against Covid-19?
  • Melanin and Vitamin D: are they related?
  • What are the recommended Vitamin D levels?
  • How Can I Increase Vitamin D Levels?
  • Is too much Vitamin D dangerous?
  • Vitamin D will not prevent COVID
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What is Vitamin D?

What is Vitamin D? Vitamin D is a nutrient that is vital for human health.  Unlike other Vitamins, however, naturally we get very little of Vitamin D from our food, but instead from our skin when it has the sun shining on it.

In the deeper levels of our skin, our cells use ultraviolet light (UV-B) to manufacture the Vitamin D precursor molecule.  This precursor then travels first to our liver, and then to our kidney, to get activated in separate steps to the form of Vitamin D that promotes our health.  This active form then travels through our blood, getting delivered to different cell types that need it [1].  For example, cells that make bone need Vitamin D so they can absorb Calcium, and without it, people suffer from soft bones in the disease caused Rickets.  

However, recent research has found that Vitamin D is important for much more than bone health, and is especially important for a healthy immune system [2,3].  During the winter, because our skin is exposed to much less sunlight, our Vitamin D levels drop.  This is thought to be the reason that winter is cold and flu season [4,5].  Many medical experts consider that there is an epidemic of Vitamin D deficiency, especially among people with dark skin [6,7].

Although we don’t generally get much Vitamin D through food, it is possible to increase our Vitamin D levels through supplementation.  Some fatty fish have Vitamin D, and long ago, it was discovered that cod liver oil could help people recover from illness; more recently it was found that Vitamin D was the active ingredient in cod liver oil [8].  Nowadays, oral Vitamin D supplementation is more frequently done by fortification of milk and infant formula, and by capsules or softgels, at either nonprescription or prescription strength.  

REFERENCES

  1. Bikle, D.  et al.  2017. Vitamin D: Production, Metabolism, and Mechanisms of Action. Endotext [Internet]. South Dartmouth (MA): MDText.com.

  2. Aronow, C.  2011. Vitamin D and the immune system. J. Investig. Med. 59:881.

  3. Bouillon, R. et al.  2019. Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions. Endocrinol. Rev. 40:1109.

  4. Cannell, J. et al.  2006. Epidemic influenza and vitamin D. Epidemiol. Infect. 134:1129.

  5. Juzeniene, A. et al.  2010. The seasonality of pandemic and non-pandemic influenzas: the roles of solar radiation and vitamin D. Int. J. Infecious. Diseases. 14:e1099.

  6. Holick, M.  2007. Vitamin D Deficiency. N. Engl. J. Med. 357:266.

  7. Harris, S.  2006.  Vitamin D and African Americans. J. Nutr. 136:1126.

  8. Cannell, J.  2008. Cod Liver Oil, Vitamin A Toxicity, Frequent Respiratory Infections, and the Vitamin D Deficiency Epidemic. Ann. Otol. Rhinol. Laryngol. 117:864.